TISSUES

Tissue expression database

RIOK2 tissues

RIOK2 [ENSP00000283109]

Serine/threonine-protein kinase RIO2; Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre- rRNA to the mature 18S rRNA . Regulates the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, most likely by PLK1, regulates this function .

Synonyms:  RIOK2,  RIOK2p,  hRIOK2,  D6RB96,  H0Y8R4 ...

Linkouts:  STRING  Pharos  UniProt

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