LMBR1L tissues
LMBR1L [ENSP00000267102]
Protein LMBR1L; Plays an essential role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway (By similarity). In association with UBAC2 and E3 ubiquitin-protein ligase AMFR, promotes the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6 (By similarity). LMBR1L stabilizes the beta- catenin destruction complex that is required for regulating CTNNB1 levels (By similarity). Acts as a LCN1 receptor and can mediate its endocytosis . ; Belongs to the LIMR family.
Synonyms: LMBR1L, LMBR1Lp, hLMBR1L, A0A024R0Y9, A0A0S2Z6E3 ...