TISSUES

Tissue expression database

ARRDC3 tissues

ARRDC3 [ENSP00000265138]

Arrestin domain-containing protein 3; Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein- coupled receptors . Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2 . Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes . ; Belongs to the arrestin family.

Synonyms:  ARRDC3,  ARRDC3p,  hARRDC3,  Q96B67,  Q96B67p ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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