RRAGB tissues
RRAGB [ENSP00000262850]
Ras-related GTP-binding protein B; Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. ; Belongs to the GTR/RAG GTP-binding protein family.
Synonyms: RRAGB, Q5VZM0, Q5VZM2, Q5VZM0p, hQ5VZM0 ...