TISSUES

Tissue expression database

RAB21 tissues

RAB21 [ENSP00000261263]

Ras-related protein Rab-21; Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (By similarity). As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis . Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion .

Synonyms:  RAB21,  RAB21p,  hRAB21,  A0A024RBA9,  Q9UL25 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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