TISSUES

Tissue expression database

RBSN tissues

RBSN [ENSP00000253699]

Rabenosyn-5; Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) . Plays a role in the recycling of transferrin receptor to the plasma membrane . ECO:0000269|PubMed:11788822, ECO:0000269|PubMed:15020713,

Synonyms:  RBSN,  A0A024R2H4,  C9JZZ1,  D6RD50,  F8WE50 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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