TISSUES

Tissue expression database

FBXL12 tissues

FBXL12 [ENSP00000247977]

F-box/LRR-repeat protein 12; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia.

Synonyms:  FBXL12,  FBXL12p,  hFBXL12,  K7EIK3,  K7EIR3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

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